Please join NIF for the next webinar at the crossroads of neuroscience and informatics.

Topic: The state of Macroconnectomes: what can these tell us about the nervous system?

Date/Time: February 5, 2013 – 11:00 am PDT (2:00 Eastern Time)

Presenter: Hongwei Dong


URL: Recording available

Macro-connectomes (connectivity matrices at the brain regions level) are essential for understanding the structure-functional relationships of different parts of the mammalian central nervous system. They are also the starting point in construction of functionally relevant networks with different levels of complexity.

The construction of macroconnectomes is a complex and time consuming task involving combined efforts from experimental neuroanatomists and neuroinformaticians. There is no completed macroconnectome of any species to date, but a substantial amount of rat and macaque connectivity data is already collated by several neuroinformatics groups. The advent of more sophisticated axonal tracing techniques promises rapid production of high quality experimental connectivity data in (rodent) animal models. Moreover, improved tools for visualization, sharing, and analysis of tract tracing data, will expectedly facilitate extraction of knowledge and assembly of connectome matrices from such data.